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1

Clinical Pharmacokinetics of Artemether and Lumefantrine (Riamet®)

Dr Gilbert Lefèvre, Mikael S. Thomsen

Journal:

Clinical Drug Investigation

Year:

1999

Language:

english

File:

PDF, 219 KB

english, 1999

2

Development and use of the strain gauge for study the constraint of tibio-femoral joint in dynamic movement: Feasibility and first results

Sobczak, S., Gilbert, B., Feipel, V., Van Sint Jan, S., Lefèvre, P., Salvia, P., Rooze, M.

Journal:

Computer Methods in Biomechanics & Biomedical Engineering

Year:

2005

Language:

english

File:

PDF, 87 KB

english, 2005

3

Characterization of effector-target conjugates for cloned human natural killer and human lymphokine activated killer cells by flow cytometry

Dr. Denis M. Callewaert, Gilbert Radcliff, Ross Waite, Janet LeFevre, M. Dave Poulik

Journal:

Cytometry Part A

Year:

1991

Language:

english

File:

PDF, 1.07 MB

english, 1991

4

Effect of renal impairment on the pharmacokinetics and pharmacodynamics of desirudin

Lefèvre, Gilbert, Duval, Martine, Gauron, Sonia, Brookman, Laurence J., Rolan, Paul E., Morris, Thomas M., Piraino, Anthony J., Morgan, John M., Palmisano, Maria, Close, Philippe

Journal:

Clinical Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 906 KB

english, 1997

5

Automated quantitative determination of the new renin inhibitor CGP 60536 by high-performance liquid chromatography

Gilbert Lefèvre, Sonia Gauron

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

6

Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet®) with concomitant administration of ketoconazole in healthy subjects

Gilbert Lefèvre, Polly Carpenter, Claire Souppart, Heinz Schmidli, Mark McClean, Daria Stypinski

Journal:

British Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

7

Novartis Malaria Initiative: best practice example of pharmaceutical industry's engagement in the fight against malaria

Gilbert Lefèvre, Anne Claire Marrast, Heiner Grueninger

Journal:

Annals of the New York Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 377 KB

english, 2011

8

Pharmacokinetics of rec-hirudin in healthy volunteers after intravenous administration

Jean-Michel A. Cardot, Gilbert Y. Lefèvre, Jacques A. Godbillon

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1994

Language:

english

File:

PDF, 441 KB

english, 1994

9

Pharmacokinetic interaction trial between co-artemether and mefloquine

Gilbert Lefèvre, Margaretha Bindschedler, Farkad Ezzet, Nicole Schaeffer, Ingo Meyer, Mikael S Thomsen

Journal:

European Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 281 KB

english, 2000

10

Binding of iralukast to serum proteins and erythrocytes: measurements using ultrafiltration and an erythrocyte partitioning method

Danielle Colussi, Carole Parisot, Gilbert Lefèvre

Journal:

European Journal of Pharmaceutical Sciences

Year:

1999

Language:

english

File:

PDF, 243 KB

english, 1999

11

Binding of artemether and lumefantrine to plasma proteins and erythrocytes

Danielle Colussi, Carole Parisot, François Legay, Gilbert Lefèvre

Journal:

European Journal of Pharmaceutical Sciences

Year:

1999

Language:

english

File:

PDF, 121 KB

english, 1999

12

Quantification of effector/target conjugation involving natural killer (NK) or lymphokine activated killer (LAK) cells by two-color flow cytometry

Gilbert Radcliff, Ross Waite, Janet LeFevre, M. Dave Poulik, Denis M. Callewaert

Journal:

Journal of Immunological Methods

Year:

1991

Language:

english

File:

PDF, 980 KB

english, 1991

13

Value and limitations of the duke criteria for the diagnosis of infective endocarditis

Gilbert Habib, Geneviève Derumeaux, Jean-François Avierinos, Jean-Paul Casalta, Fadi Jamal, Françoise Volot, Marc Garcia, Jean Lefevre, Frédéric Biou, Alexandre Maximovitch-Rodaminoff, P.E Fournier, P

Journal:

Journal of the American College of Cardiology

Year:

1999

Language:

english

File:

PDF, 152 KB

english, 1999

14

Steady-State Pharmacokinetics of Rivastigmine in Patients with Mild to Moderate Alzheimer’s Disease Not Affected by Co-Administration of Memantine

Shua-Haim, Joshua, Smith, Juanita, Picard, Franck, Sedek, Greg, Athalye, Sandeep, Pommier, Françoise, Lefèvre, Gilbert

Journal:

Clinical Drug Investigation

Year:

2008

Language:

english

File:

PDF, 164 KB

english, 2008

15

Pharmacokinetics and Bioavailability of the Novel Rivastigmine Transdermal Patch Versus Rivastigmine Oral Solution in Healthy Elderly Subjects

Lefèvre, Gilbert, Pommier, Françoise, Sędek, Greg, Allison, Mark, Huang, Hsun-Lun Aaron, Kiese, Beate, Ho, Yu-Yun, Appel-Dingemanse, Silke

Journal:

Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 111 KB

english, 2008

16

Protein Binding in Plasma of Valsartan, a New Angiotensin II Receptor Antagonist

Colussi, Danielle M., Parisot, Carole, Rossolino, Maria L., Brunner, Linda A., Lefèvre, Gilbert Y.

Journal:

Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 1.10 MB

english, 1997

17

Differences in the pharmacokinetics of currently approved antimalarial drugs in uncomplicated malaria patients compared to healthy subjects

Jay Prakash Jain, Suresh B Lakshminarayana, Gilbert Lefèvre…

Journal:

Malaria Journal

Year:

2012

Language:

english

File:

PDF, 72 KB

english, 2012

18

Understanding the pharmacokinetics of Coartem®

Abdoulaye Djimdé, Gilbert Lefèvre

Journal:

Malaria Journal

Year:

2009

Language:

english

File:

PDF, 213 KB

english, 2009

19

Evaluation of two novel tablet formulations of artemether-lumefantrine (Coartem®) for bioequivalence in a randomized, open-label, two-period study

Lefèvre, Gilbert, Bhad, Prafulla, Jain, Jay, Kalluri, Sampath, Cheng, Yi, Dave, Hardik, Stein, Daniel S

Journal:

Malaria Journal

Year:

2013

Language:

english

File:

PDF, 221 KB

english, 2013

20

Rivastigmine exposure provided by a transdermal patch versus capsules

Mercier, François, Lefèvre, Gilbert, Aaron Huang, Hsun-Lun, Schmidli, Heinz, Amzal, Billy, Appel-Dingemanse, Silke

Journal:

Current Medical Research and Opinion

Year:

2007

Language:

english

File:

PDF, 238 KB

english, 2007

21

Announcement

Jego, Christophe, Schuster, Iris, Medall, Christine, Lefevre, Jean, Franceschi, Frederic, Vailloud, Jean-Marie, Ferracci, Ange, DeHaro, Jean-Claude, Dijane, Pierre, Habib, Gilbert H

Journal:

Year:

1986

Language:

english

File:

PDF, 66 KB

english, 1986

22

872-5 Incidence of diastolic dyssynchrony in dilated cardiomyopathy and effects of biventricular pacing

Jego, Christophe, Schuster, Iris, Medall, Christine, Lefevre, Jean, Franceschi, Frederic, Vailloud, Jean-Marie, Ferracci, Ange, DeHaro, Jean-Claude, Dijane, Pierre, Habib, Gilbert H

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 105 KB

english, 2004

23

P4-410

Shua-Haim, Joshua R., Smith, Juanita M., Lefevre, Gilbert, Frank, Picard, Sedek, Greg, Athalye, Sandeep, Pommier, Francoise

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 56 KB

english, 2006

24

3.P.294 Compared modulation of porcine VSMC proliferation and gelatinase production by IFNγ, TGFβ and PDGF

Gilbert, M.A., Lindenmeyer, F., Lefèvre, F., La Bonnardière, C., Drouet, L.

Journal:

Atherosclerosis

Year:

1997

Language:

english

File:

PDF, 159 KB

english, 1997

25

Anti-idiotypic antibodies to a monoclonal antibody raised against anti-Müllerian hormone exhibit anti-Müllerian biological activity

Lefèvre, Gilbert, Tran, Dien, Hoebeke, Johan, Josso, Nathalie

Journal:

Molecular and Cellular Endocrinology

Year:

1989

Language:

english

File:

PDF, 1.09 MB

english, 1989

26

Modeling Carbon to Nitrogen and Carbon to Chlorophyll a Ratios in the Ocean at Low Latitudes: Evaluation of the Role of Physiological Plasticity

Nathalie Lefèvre, Arnold H. Taylor, Francis J. Gilbert and Richard J. Geider

Journal:

Limnology and Oceanography

Year:

2003

Language:

english

File:

PDF, 590 KB

english, 2003

27

Chemical reactivity in organized medium: building up a two-dimensional polymer

Lefevre, Didier, Porteu, Florence, Balog, Peter, Roulliay, Monique, Zalczer, Gilbert, Palacin, Serge

Journal:

Year:

1993

Language:

english

File:

PDF, 3.63 MB

english, 1993

28

Direct Micro-Radioimmunoassay of the New Renin Inhibitor Cgp 60536

Lefèvre, Gilbert, Duval, Martine, Poncin, Alain

Journal:

Journal of Immunoassay

Year:

2000

Language:

english

File:

PDF, 606 KB

english, 2000

29

Similar Rivastigmine Pharmacokinetics and Pharmacodynamics in Japanese and White Healthy Participants Following the Application of Novel Rivastigmine Patch

Lefèvre, Gilbert, Büche, Monika, Sedek, Greg, Maton, Steve, Enz, Albert, Lorch, Ulrike, Sagan, Cyriaque, Appel-Dingemanse, Silke

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

30

Pharmacokinetics of a Rivastigmine Transdermal Patch Formulation in Healthy Volunteers: Relative Effects of Body Site Application

Lefèvre, Gilbert, Sędek, Greg, Huang, Hsun-Lun Aaron, Saltzman, Marc, Rosenberg, Mitchell, Kiese, Beate, Fordham, Peter

Journal:

Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 115 KB

english, 2007

31

Direct Microtitre Plate Radioimmunoassay of Savoxepine in Unextracted Plasma

Lefèvre, Gilbert, Duval, Martine, Botta, Luigi, Godbillon, Jacques

Journal:

Journal of Immunoassay

Year:

1996

Language:

english

File:

PDF, 583 KB

english, 1996

32

Le chômage partiel en France et en Allemagne: des logiques institutionnelles aux pratiques d'entreprise

Lallement, Michel, Lefèvre, Gilbert

Journal:

Loisir et Société / Society and Leisure

Year:

1997

Language:

english

File:

PDF, 1.31 MB

english, 1997

33

Spiroindolone KAE609 for Falciparum and Vivax Malaria

White, Nicholas J., Pukrittayakamee, Sasithon, Phyo, Aung Pyae, Rueangweerayut, Ronnatrai, Nosten, François, Jittamala, Podjanee, Jeeyapant, Atthanee, Jain, Jay Prakash, Lefèvre, Gilbert, Li, Ruobing,

Journal:

New England Journal of Medicine

Year:

2014

Language:

english

File:

PDF, 692 KB

english, 2014

34

A first-in-human randomized, double-blind, placebo-controlled, single- and multiple-ascending oral dose study of novel spiroindolone KAE609, to assess the safety, tolerability and pharmacokinetics in healthy adult volunteers

Leong, Joel, Li, Ruobing, Jain, Jay, Lefèvre, Gilbert, Magnusson, Baldur, Diagana, Thierry, Pertel, Peter

Journal:

Malaria Journal

Year:

2014

Language:

english

File:

PDF, 254 KB

english, 2014

35

A phase 1 evaluation of the pharmacokinetic/pharmacodynamic interaction of the antimalarial agents KAE609 and piperaquine (PPQ)

Stein, Daniel S, Jain, Jay, Lickliter, Jason, Kangas, Michael, Machineni, Surendra, Griffin, Paul, Lefevre, Gilbert

Journal:

Malaria Journal

Year:

2014

Language:

english

File:

PDF, 211 KB

english, 2014

36

Increased systemic exposures of artemether and dihydroartemisinin in infants under 5 kg with uncomplicated Plasmodium falciparum malaria treated with artemether-lumefantrine (Coartem®)

Tiono, Alfred B, Tinto, Halidou, Alao, Maroufou J, Meremikwu, Martin, Tshefu, Antoinette, Ogutu, Bernhards, Ouedraogo, Alphonse, Lingani, Moussa, Cousin, Marc, Lefèvre, Gilbert, Jain, Jay Prakash, Dup

Journal:

Malaria Journal

Year:

2015

Language:

english

File:

PDF, 511 KB

english, 2015

37

Open-Label, Single-Dose, Parallel-Group Study in Healthy Volunteers To Determine the Drug-Drug Interaction Potential between KAE609 (Cipargamin) and Piperaquine

Stein, Daniel S., Jain, Jay Prakash, Kangas, Michael, Lefèvre, Gilbert, Machineni, Surendra, Griffin, Paul, Lickliter, Jason

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 693 KB

english, 2015

38

Modeling carbon to nitrogen and carbon to chlorophyll a ratios in the ocean at low latitudes: Evaluation of the role of physiological plasticity

Lefèvre, Nathalie, Taylor, Arnold H., Gilbert, Francis J., Geider, Richard J.

Journal:

Limnology and Oceanography

Year:

2003

Language:

english

File:

PDF, 471 KB

english, 2003

39

Pharmacokinetic Modeling to Simulate the Concentration-Time Profiles After Dermal Application of Rivastigmine Patch

Nozaki, Sachiko, Yamaguchi, Masayuki, Lefèvre, Gilbert

Journal:

Journal of Pharmaceutical Sciences

Year:

2016

Language:

english

File:

PDF, 2.03 MB

english, 2016

40

Plasma Protein Binding of Letrozole, a New Nonsteroidal Aromatase Enzyme Inhibitor

Colussi, Danielle M., Parisot, Carole Y., Lefèvre, Gilbert Y.

Journal:

Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 1.21 MB

english, 1998

41

Lower artemether, dihydroartemisinin and lumefantrine concentrations during rifampicin-based tuberculosis treatment

Lamorde, Mohammed, Byakika-Kibwika, Pauline, Mayito, Jonathan, Nabukeera, Lillian, Ryan, Mairin, Hanpithakpong, Warunee, Lefèvre, Gilbert, Back, David J., Khoo, Saye H., Merry, Concepta

Journal:

Year:

2013

Language:

english

File:

PDF, 139 KB

english, 2013

42

Effects of Renal Impairment on Steady-State Plasma Concentrations of Rivastigmine: A Population Pharmacokinetic Analysis of Capsule and Patch Formulations in Patients with Alzheimer’s Disease

Lefèvre, Gilbert, Callegari, Francesca, Gsteiger, Sandro, Xiong, Yuan

Journal:

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

43

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis

Kloprogge, Frank, Workman, Lesley, Borrmann, Steffen, Tékété, Mamadou, Lefèvre, Gilbert, Hamed, Kamal, Piola, Patrice, Ursing, Johan, Kofoed, Poul Erik, Mårtensson, Andreas, Ngasala, Billy, Björkman,

Journal:

Year:

2018

Language:

english

File:

PDF, 7.88 MB

english, 2018

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